Ativan is an anti-anxiety drug used to treat panic attacks, neurosis-like states and various disorders caused by stress.
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The active substance Lorazepam has a central muscle relaxant, hypnotic, anxiolytic, sedative, anticonvulsant and antiemetic effect.
Lorazepam refers to medium-duration drugs that are used to treat panic attacks and to reduce anxiety. According to the instructions, Ativan is not effective in acute delusional, hallucinatory, affective disorders, and in the treatment of psychotic disorders such as depression or related anxiety, it is not recommended to take it as the main drug.
Long-term reception of Ativan can lead to tolerance and a gradual decrease in effectiveness, as well as to the development of drug dependence and addiction.
- conditions of a psychoreactive nature;
- the treatment of extreme nervous emotional tension and anxiety, in cases of psychosomatic disorders, for the relief of a panic attack;
- schizophrenic states;
- symptoms of VSD
- a state of insomnia, which appeared due to stress and increased anxiety;
- the treatment of epileptic conditions (the drug is used as part of a complex treatment);
- during depressive states when signs of anxiety are observed (used with extreme caution!);
- headaches that are accompanied by increased muscle tension;
- elimination of neurosis-like states and neuroses when tension and feelings of anxiety are observed;
- prevention of nausea and vomiting that occur during chemotherapy.
- hypersensitivity to the components of the drug;
- angle-closure glaucoma;
- depressive neuroses;
- myasthenia gravis;
- intoxication in acute form;
- pregnancy and lactation;
- age up to 13 years (efficacy and safety have not been established);
The drug is used with caution in the following conditions: during liver damage; heart failure; during hypertension; with multiple sclerosis; with reduced body weight.
Ativan enhances the effect of CNS depressants, including phenothiazines, narcotic analgesics, barbiturates, antidepressants, hypnotics, anticonvulsants, antihistamines with sedative effect. The drug potentiates the effect of general and local anesthetics, enhances the effect of curare-like drugs. When the drug is used simultaneously with alcohol, it may cause paradoxical reactions (psychomotor agitation, aggressive behavior, a state of pathological intoxication) in addition to increasing the depressing effect on the central nervous system. Nicotine suppresses the activity of lorazepam (accelerates its metabolism).
Method of application of Ativan
Adults are usually prescribed Ativan in a daily dose of 2 mg, divided into 3 doses. At the same time, half of the daily dose is recommended to be taken in the morning and afternoon, and the second half - just before bedtime.
Depending on the symptoms, the dosage of Ativan may vary: 1 mg to 3 times a day. The maximum daily dose when ingested is 6 mg.
The abrupt withdrawal of Lorazepam may cause the development of the withdrawal syndrome.
Side effects of Ativan
According to the instructions, Ativan rarely causes side effects and, judging by the reviews, the therapy carried out by the drug is usually well tolerated. The most common side effects include the following violations:
- Central nervous system: increased fatigue, muscle weakness, ataxia, dizziness, amnesia;
- Digestive system: constipation, dry mouth, nausea, impaired appetite and liver function, dysphagia, diarrhea.
Also, the reception of Ativan can lead to changes in the picture of peripheral blood and cause minor allergic reactions in the form of itching and skin rash. According to the reviews, venous thrombosis and phlebitis are among the most likely local reactions with intravenous administration.
Undesirable side effects with Ativan therapy are most often observed at the beginning of treatment or when the doses of the drug recommended by the instructions are exceeded.
Pregnancy and breastfeeding
The drug is prohibited during pregnancy. It can be taken only for vital indications in individual cases, as it contributes to the development of pathologies and anomalies in the embryo / fetus. A particularly strong destructive effect is observed during therapy in the first months of pregnancy. Treatment with Ativan in the last stages causes pathology of the central nervous system in the unborn child. Systematic use of drugs during gestation forms a child's dependence on the drug and withdrawal syndrome after discontinuation of therapy.
Nursing women should take into account that Lorazepam is excreted in milk. Therefore, if there is a need for the use of Ativan during lactation, it should be canceled.